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Famotidine is predicted to decrease the absorption of itraconazole. Itraconazole is predicted to increase the exposure to felodipine. Itraconazole is predicted to increase the exposure to fentanyl.
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It is an alternative form of therapy to the oral medications. The mixture of the medication is a combination of several compounds having properties that dilate the arteries of the penis, allowing blood to flow in to cause an erection.Serious, potentially fatal cardiovascular effects reported rarely. Consider whether patients with underlying cardiovascular disease e. Use not recommended in patients with pulmonary veno-occlusive disease.
Erectile responsiveness: Approximately 2 hours. Erectile responsiveness: 14-20 minutes, self-recorded in the home setting. Appears to be widely distributed in the body.
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Once daily use is not recommended. The maximum recommended dosing frequency is once per day in most patients.
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See the end of this Patient Information leaflet for a complete list of ingredients in Itraconazole capsules. Itraconazole can pass into your breast milk. You and your healthcare provider should decide if you will take Itraconazole capsules or breastfeed.
Following a single oral dose, effects were obtained within 30 minutes. Improved erection up to 36 hours. Metabolized in the liver, principally by CYP3A4, to inactive metabolites.
In the rare event you have a painful or prolonged erection lasting 4 or more hours, stop using this drug and get medical help right away, or permanent problems could occur. A very serious allergic reaction to this drug is rare.
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